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The National Institute of Standards and Technology (NIST) has issued its first reference standards for nanoscale particles targeted for the biomedical research community—literally “gold standards” for labs studying the biological effects of nanoparticles. The three new materials, gold spheres nominally 10, 30 and 60 nanometers in diameter, were developed in cooperation with the National Cancer Institute’s Nanotechnology Characterization Laboratory (NCL).

Nanosized particles are the subject of a great deal of biological research, in part because of concerns that in addition to having unique physical properties due to their size, they also may have unique biological properties. On the negative side, nanoparticles may have special toxicity issues. On the positive side, they also are being studied as vehicles for targeted drug delivery that have the potential to revolutionize cancer treatments. Research in the field has suffered from a lack of reliable nanoscale measurement standards, both to ensure consistency of data from one lab to the next and to verify the performance of measurement instruments and analytic techniques.

False color scanning electron micrograph (250,000 times magnification) showing the gold nanoparticles created by NIST and the National Cancer Institute’s Nanotechnology Characterization Laboratory for use as reference standards in biomedical research laboratories.The new NIST reference materials are citrate-stabilized nanosized gold particles in a colloidal suspension in water. They have been extensively analyzed by NIST scientists to assess particle size and size distribution by multiple techniques for dry-deposited, aerosol and liquid-borne forms of the material. Dimensions were measured using six independent methods—including atomic force microscopy (AFM), transmission electron microscopy (TEM), scanning electron microscopy (SEM), differential mobility analysis (DMA), dynamic light scattering (DLS), and small-angle X-ray scattering (SAXS). At the nanoscale in particular, different measurement techniques can and will produce different types of values for the same particles.

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Nanotechnology companies, nurtured on billions of dollars in government grants and venture investments through most of this decade, are getting ready to go public.

Being near to taking such a step is another stage in the evolution of nanotechnology, the science of materials measured at billionths of a meter, or 1/500th of a human hair.

 

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Researchers in Israel say they have succeeded in putting a version of the Bible on a chip smaller than a pinhead. Its 300,000 words in Hebrew were inscribed on a silicon surface at the Haifa Institute of Technology.

Scientists say the aim of the project is to increase young people’s interest in nanoscience and nanotechnology.

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Bellingham, WA — Micro- and nanolithography practitioners will share their up-to-the-minute research results and latest innovations at the SPIE Advanced Lithography conference in San Jose, CA, USA, in February. Topics range from state-of-the-art lithographic tools and technologies, resists, metrology, and materials characterization, to design and process integration, including progress of extending these technologies or switching to emerging alternatives. The event will be held 24-29 February 2008 in the San Jose Convention Center.

SPIE Advanced Lithography provides a rich networking opportunity for the international community and is known as a forum for high-quality technical presentations. More than 700 papers will be presented in five technical conferences. Of high interest are papers on nanoimprint, electron-beam direct write, parallel e-beam systems, extreme-UV systems, directed self assembly, molecular resists, EUV resists, double patterning, and high-index immersion lithography.

Three plenary talks are scheduled:

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A new strategic plan for the work of the National Nanotechnology Initiative has just been released by the interagency Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the National Science and Technology Council’s Committee on Technology with support from the National Nanotechnology Coordination Office (NNCO). The 2007 NNI Strategic Plan describes the vision, goals, and priorities of the NNI to ensure that the United States derives growing economic benefits and improved quality of life for its citizens and remains a global leader in nanotechnology R&D in the years to come.

According to NNCO Director Clayton Teague, periodic reexamination of the NNI Strategic Plan is essential, given the dynamic nature of the field. The 21st Century Nanotechnology Research and Development Act of 2003 calls for the NNI Strategic Plan to be updated every third year; the plan just released updates and replaces the December 2004 plan.

“This strategic plan presents an overview of the NNI for the public and will facilitate achievement of the NNI vision by offering guidance for agency leaders, program managers, and the research community in their nanotechnology R&D investments and activities,” said Dr. Teague. He noted that the new plan reflects the consensus of the 25 NNI participating agencies as to the goals and priorities of the NNI and provides a framework within which each agency will carry out its own mission-related nanotechnology programs, as well as a path that will sustain coordination of interagency activities. In addition to specifying high-level goals, the plan identifies activities aimed at accomplishing those goals. The plan also identifies major subject areas, or program component areas (PCAs), in which investments are needed to ensure the success of the initiative. Finally, the plan identifies a number of representative high-impact application opportunities that cut across the NNI program component areas and that align with the competencies and missions of participating agencies.

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