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System is invisible to the immune system, preventing response
News source: University of California - Los Angeles, via AAAS EurekAlertUsing nanotechnology, scientists from UCLA and Northwestern University have developed a localized and controlled drug delivery method that is invisible to the immune system, a discovery that could provide newer and more effective treatments for cancer and other diseases.

…The researchers used nanoscale polymer films, about four nanometers per layer, to build a sort of matrix or platform to hold and slowly release an anti-inflammatory drug. The films are orders of magnitude thinner than conventional drug deliver coatings, said Genhong Cheng, a researcher at UCLA’s Jonsson Comprehensive Cancer Center and one of the study’s authors…

“Using this system, drugs could be released slowly and under control for weeks or longer,” said Cheng, a professor of microbiology, immunology and molecular genetics. “A drug that is given orally or through the bloodstream travels throughout the system and dissipates from the body much more quickly. Using a more localized and controlled approach could limit side effects, particularly with chemotherapy drugs.” Continue reading ‘Copolymeric Nanofilm Platform for Controlled and Localized Therapeutic Delivery’ »